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Research Finds Getting Less Than Nine Hours of Sleep Nightly Associated with Cognitive Difficulties, Mental Problems, and Less Gray Matter in Certain Brain Regions

Elementary school-age children who get less than nine hours of sleep per night have significant differences in certain brain regions responsible for memory, intelligence, and well-being compared to those who get the recommended 9-12 hours of sleep per night, according to a new study led by University of Maryland School of BOB体育 (UMSOM) researchers. Such differences correlated with greater mental health problems like depression, anxiety, and impulsive behaviors in those who lacked sleep. Inadequate sleep was also linked to cognitive difficulties with memory, problem solving and decision making. The findings were published today in the journal Lancet Child & Adolescent Health.

The recommends that children aged 6-12 years of age sleep 9-12 hours per night on a regular basis to promote optimal health. Up until now, no studies have examined the long-lasting impact of insufficient sleep on the neurocognitive development of pre-teens.

To conduct the study, the researchers examined data that were collected from more than 8,300 children aged 9-10 years, who were enrolled in the  study. They examined MRI images, medical records, and surveys completed by the participants and their parents at the time of enrollment and at a two-year follow-up visit at 11-12 years of age. Funded by the National Institutes of Health (NIH), the ABCD study is the largest long-term study of brain development and child health in the US.

鈥淲e found that children who had insufficient sleep, less than nine hours per night, at the beginning of the study had less grey matter or smaller volume in certain areas of the brain responsible for attention, memory, and inhibition control, compared to those with healthy sleep habits,鈥� said study corresponding author Ze Wang, PhD, Professor of Diagnostic Radiology and Nuclear BOB体育 at UMSOM. 鈥淭hese differences persisted after two years, a concerning finding that suggests long-term harm for those who do not get enough sleep.鈥�

This study offers some of the first findings to demonstrate the potential long-term impact of lack of sleep on neurocognitive development in children. It also provides substantial support for the current sleep recommendations in children, according to Dr. Wang and his colleagues.  

In follow-up assessments, the research team found that participants in the sufficient sleep group tended to gradually sleep less over two years, which is normal as children move into their teen years, whereas sleep patterns of participants in the insufficient sleep group did not change much. The researchers controlled for socioeconomic status, gender, puberty status, and other factors that could impact how much a child sleeps and affect brain and cognition.

鈥淲e tried to match the two groups as closely as possible to help us more fully understand the long-term impact on too little sleep on the pre-adolescent brain,鈥� Dr. Wang said. 鈥淎dditional studies are needed to confirm our finding and to see whether any interventions can improve sleep habits and reverse the neurological deficits.鈥�

The encourages parents to promote good sleep habits in their children. Their tips include making sufficient sleep a family priority, sticking with a regular sleep routine, encouraging physical activity during the day, limiting screen time, and eliminating screens completely an hour before bed.

The study was funded by NIH. Fan Nils Yang, PhD, a post-doctoral fellow in Dr. Wang鈥檚 laboratory is a study co-author. Weizhen Xie, PhD, a researcher at the National Institute of Neurological Disorders and Stroke, is also a study co-author. UMSOM faculty members Thomas Ernst, PhD, and Linda Chang, MD, MS, are at the Baltimore site but were not involved in the data analysis of this new study.

鈥淭his is a crucial study finding that points to the importance of doing long-term studies on the developing child鈥檚 brain,鈥� said E. Albert Reece, MD, PhD, MBA, Executive Vice President for Medical Affairs, UM Baltimore, and the John Z. and Akiko K. Bowers Distinguished Professor and Dean, University of Maryland School of BOB体育. "Sleep can often be overlooked during busy childhood days filled with homework and extracurricular activities. Now we see how detrimental that can be to a child鈥檚 development.鈥�

About the University of Maryland School of BOB体育

Now in its third century, the University of Maryland School of BOB体育 was chartered in 1807 as the first public medical school in the United States. It continues today as one of the fastest growing, top-tier biomedical research enterprises in the world -- with 46 academic departments, centers, institutes, and programs, and a faculty of more than 3,000 physicians, scientists, and allied health professionals, including members of the National Academy of BOB体育 and the National Academy of Sciences, and a distinguished two-time winner of the Albert E. Lasker Award in Medical Research. With an operating budget of more than $1.3 billion, the School of BOB体育 works closely in partnership with the University of Maryland Medical Center and Medical System to provide research-intensive, academic, and clinically based care for nearly 2 million patients each year. The School of BOB体育 has nearly $600 million in extramural funding, with most of its academic departments highly ranked among all medical schools in the nation in research funding. As one of the seven professional schools that make up the University of Maryland, Baltimore campus, the School of BOB体育 has a total population of nearly 9,000 faculty and staff, including 2,500 students, trainees, residents, and fellows. The combined School of BOB体育 and Medical System (鈥淯niversity of Maryland BOB体育鈥�) has an annual budget of over $6 billion and an economic impact of nearly $20 billion on the state and local community. The School of BOB体育, which ranks as the 8th highest among public medical schools in research productivity (according to the Association of American Medical Colleges profile) is an innovator in translational medicine, with 606 active patents and 52 start-up companies. In the latest U.S. News & World Report ranking of the Best Medical Schools, published in 2021, the UM School of BOB体育 is ranked #9 among the 92 public medical schools in the U.S., and in the top 15 percent (#27) of all 192 public and private U.S. medical schools. The School of BOB体育 works locally, nationally, and globally, with research and treatment facilities in 36 countries around the world. Visit medschool.umaryland.edu